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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSNK2A1
All Species:
38.48
Human Site:
Y257
Identified Species:
52.92
UniProt:
P68400
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P68400
NP_001886.1
391
45144
Y257
G
T
E
D
L
Y
D
Y
I
D
K
Y
N
I
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001112211
397
46613
Y257
G
T
E
D
L
Y
D
Y
I
D
K
Y
N
I
E
Dog
Lupus familis
XP_534375
403
46681
Y257
G
T
E
D
L
Y
D
Y
I
D
K
Y
N
I
E
Cat
Felis silvestris
Mouse
Mus musculus
Q60737
391
45143
Y257
G
T
E
D
L
Y
D
Y
I
D
K
Y
N
I
E
Rat
Rattus norvegicus
P19139
391
45055
Y257
G
T
E
D
L
Y
D
Y
I
D
K
Y
N
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507666
350
41142
K230
L
A
S
M
I
F
R
K
E
P
F
F
H
G
Q
Chicken
Gallus gallus
P21868
391
45172
Y257
G
T
E
D
L
Y
D
Y
I
D
K
Y
N
I
E
Frog
Xenopus laevis
P28020
392
45169
Y257
G
T
E
D
L
Y
D
Y
I
D
K
Y
N
I
E
Zebra Danio
Brachydanio rerio
NP_001002164
393
45422
Y257
G
T
E
D
L
Y
D
Y
I
D
K
Y
N
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08181
336
39941
G217
S
L
D
M
W
S
L
G
C
M
L
A
S
M
I
Honey Bee
Apis mellifera
XP_393260
350
41645
F225
C
M
L
A
S
M
I
F
R
K
E
P
F
F
H
Nematode Worm
Caenorhab. elegans
P18334
360
42239
Q240
H
G
H
D
N
Y
D
Q
L
V
R
I
A
K
V
Sea Urchin
Strong. purpuratus
XP_785475
398
46271
Y255
G
T
D
E
L
Y
E
Y
L
D
K
Y
Q
I
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P28523
332
39212
L213
Y
S
L
D
M
W
S
L
G
C
M
F
A
G
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q08467
333
39240
G214
S
L
D
M
W
S
L
G
C
M
F
A
G
M
I
Baker's Yeast
Sacchar. cerevisiae
P19454
339
39385
Y220
L
L
V
N
L
N
Q
Y
D
Y
S
L
D
L
W
Red Bread Mold
Neurospora crassa
Q8TG13
336
39621
S217
S
L
G
A
M
F
A
S
M
I
F
R
K
E
P
Conservation
Percent
Protein Identity:
100
N.A.
90.4
97
N.A.
97.4
98.4
N.A.
75.4
97.9
94.9
89
N.A.
75.9
79.5
72.8
78.3
Protein Similarity:
100
N.A.
92.1
97
N.A.
98.7
98.9
N.A.
82.6
98.9
97.1
93.8
N.A.
81.8
86.1
82.3
87.1
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
0
100
100
100
N.A.
0
0
20
66.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
33.3
100
100
100
N.A.
20
13.3
33.3
93.3
Percent
Protein Identity:
N.A.
65.2
N.A.
63.4
49.8
61.1
Protein Similarity:
N.A.
74.9
N.A.
75.4
63.6
72.8
P-Site Identity:
N.A.
6.6
N.A.
0
13.3
0
P-Site Similarity:
N.A.
33.3
N.A.
13.3
33.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
12
0
0
6
0
0
0
0
12
12
0
0
% A
% Cys:
6
0
0
0
0
0
0
0
12
6
0
0
0
0
0
% C
% Asp:
0
0
18
59
0
0
53
0
6
53
0
0
6
0
0
% D
% Glu:
0
0
48
6
0
0
6
0
6
0
6
0
0
6
53
% E
% Phe:
0
0
0
0
0
12
0
6
0
0
18
12
6
6
0
% F
% Gly:
53
6
6
0
0
0
0
12
6
0
0
0
6
12
0
% G
% His:
6
0
6
0
0
0
0
0
0
0
0
0
6
0
6
% H
% Ile:
0
0
0
0
6
0
6
0
48
6
0
6
0
53
12
% I
% Lys:
0
0
0
0
0
0
0
6
0
6
53
0
6
6
0
% K
% Leu:
12
24
12
0
59
0
12
6
12
0
6
6
0
6
0
% L
% Met:
0
6
0
18
12
6
0
0
6
12
6
0
0
12
6
% M
% Asn:
0
0
0
6
6
6
0
0
0
0
0
0
48
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
6
0
6
0
0
6
% P
% Gln:
0
0
0
0
0
0
6
6
0
0
0
0
6
0
6
% Q
% Arg:
0
0
0
0
0
0
6
0
6
0
6
6
0
0
0
% R
% Ser:
18
6
6
0
6
12
6
6
0
0
6
0
6
0
0
% S
% Thr:
0
53
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
6
0
0
0
0
0
0
6
0
0
0
0
6
% V
% Trp:
0
0
0
0
12
6
0
0
0
0
0
0
0
0
6
% W
% Tyr:
6
0
0
0
0
59
0
59
0
6
0
53
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _